Facts about Langerhans Cell

1. 05

   The surface of Langerhans cells displays CD1a molecules, which are used clinically as a key marker to identify these cells in tissue samples.

   Langerhans CellJun 7shareimmunologybiologyskin
2. 04

   Abnormal proliferation of Langerhans cells causes a rare disease called Langerhans cell histiocytosis, which can affect bones, skin, and other organs.

   Langerhans CellJun 7shareimmunologydiseasepathology
3. 03

   Birbeck granules, tennis racket-shaped organelles found inside Langerhans cells, are a defining ultrastructural feature used to identify them under electron microscopy.

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4. 02

   Paul Langerhans first described these epidermal cells in 1868 while studying the skin as a medical student in Berlin.

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5. 01

   Dendritic Langerhans cells reside in the epidermis and act as sentinel immune cells that detect and present antigens to T lymphocytes.

   Langerhans CellJun 7shareimmunologybiologyskin