Facts about Pacemaker Cell

1. 07

   Latent pacemakers in the atrioventricular node fire at 40-60 beats per minute, serving as a backup if the sinoatrial node fails.

   Pacemaker CellSep 10sharebiologyphysiologycardiology
2. 06

   Pacemaker cells in the sinoatrial node fire at a baseline rate of 60-100 beats per minute when isolated from autonomic nervous system influence.

   Pacemaker CellJul 7sharebiologymeasurementphysiology
3. 05

   Autonomic nervous system input modulates pacemaker cell firing rate, with sympathetic stimulation accelerating and parasympathetic stimulation slowing the heart.

   Pacemaker CellJun 7sharebiologyphysiologyneuroscience
4. 04

   In pacemaker cells, the action potential upstroke is driven primarily by calcium ions rather than the fast sodium channels used by working cardiac muscle cells.

   Pacemaker CellJun 7sharebiologyphysiologycardiology
5. 03

   Cardiac pacemaker cells lack a stable resting membrane potential, unlike most other excitable cells that maintain a fixed resting state.

   Pacemaker CellJun 7sharebiologycardiologyphysiology
6. 02

   Funny current (If), carried by HCN channels, drives the slow diastolic depolarization that gives pacemaker cells their automaticity.

   Pacemaker CellJun 7sharebiologycardiologyelectrophysiology
7. 01

   The sinoatrial node contains pacemaker cells that spontaneously depolarize, generating the electrical impulses that set the heart's rhythm.

   Pacemaker CellJun 7sharebiologycardiacphysiology